Posted on 10 April 2013.
Here are some things I am doing to lose 30lbs and become healthy! I will be on a 30 day fitness challenge that will progress into a 60 day fitness challenge!?
Tags: Health Medical Pharma, Support Groups, Hospitality Recreation, fitness challengeSource: http://losingweightintentionally.com/weight-loss-tips-30-days-of-health-fitness/
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Radmilo Bogdanovic, brother of Ljubisa Bogdanovic cries in village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. Ljubisa Bogdanovic a 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in a quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. Belgrade emergency hospital spokeswoman Nada Macura said the man, identified as Ljubisa Bogdanovic, used a handgun in the shooting spree at five houses. The dead included six women. (AP Photo/Darko Vojinovic)
Radmilo Bogdanovic, brother of Ljubisa Bogdanovic cries in village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. Ljubisa Bogdanovic a 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in a quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. Belgrade emergency hospital spokeswoman Nada Macura said the man, identified as Ljubisa Bogdanovic, used a handgun in the shooting spree at five houses. The dead included six women. (AP Photo/Darko Vojinovic)
Police officers carry a body in village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. A 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in the quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. Belgrade emergency hospital spokeswoman Nada Macura said the man, identified as Ljubisa Bogdanovic, used a handgun in the shooting spree at five houses. The dead included six women. (AP Photo/Darko Vojinovic)
Serbian police officers guard houses in the village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. A 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in the quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. Belgrade emergency hospital spokeswoman Nada Macura said the man, identified only as Ljubisa B., used a handgun in the shooting spree at five houses. The dead included six women. (AP Photo/Darko Vojinovic)
A police tape is seen on the road near a house in village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. A 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in a quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. (AP Photo/Darko Vojinovic)
Police officers guard a house in village of Velika Ivanca, Serbia, Tuesday, April 9, 2013. A 60-year-old man gunned down 13 people, including a baby, in a house-to-house rampage in a quiet village on Tuesday before trying to kill himself and his wife, police and hospital officials said. (AP Photo/Darko Vojinovic)
VELIKA IVANCA, Serbia (AP) ? He went from house to house in the village at dawn, cold-bloodedly gunning down his mother, his son, a 2-year-old cousin and 10 other neighbors. Terrified residents said if a police patrol car hadn't shown up, they all would have been dead.
Police said they knew of no motive yet in the carnage Tuesday that left six men, six women and a child dead in Velika Ivanca, a Serbian village 50 kilometers (30 miles) southeast of Belgrade.
After the rampage, police said suspect Ljubisa Bogdanovic, a 60-year-old who saw action in one of the bloodiest sieges of the Balkan wars, turned his gun on himself and his wife as authorities closed in. Both were in grave condition at a hospital in the Serbian capital.
In the small lush village surrounded by fruit trees, the suspect's older brother Radmilo broke down in tears, unable to explain why the massacre had happened.
"Why did he do it? ... I still can't believe it," he said sobbing, covering his face with his hands. "He was a model of honesty."
"As a child, he was a frightened little boy. I used to defend him from other children. He couldn't even slaughter a chicken," he said.
But he said his brother had changed after serving in the army during a brutal Serb-led offensive against the eastern Croatian town of Vukovar in 1992 ? the worst bloodshed during Croatia's 1991-95 war for independence.
"The war had burdened him," Radmilo told The Associated Press in an interview. "He used to tell me: God forbid you live through what I went through ... Something must have clicked in his head for him to do this."
Twelve people in the village were killed immediately between 5 a.m. and 5:30 a.m. and one person died later in a Belgrade hospital, Serbian police chief Milorad Veljovic said.
"Most of the victims were shot while they were asleep," Veljovic told reporters. "The most harrowing scene discovered by police was the dead bodies of a young mother and her 2-year-old son."
The suspect had lost his job last year at a wood-processing factory, the police chief said.
Although such mass shootings are relatively rare in Serbia, weapons are readily available, mostly from the 1990s wars in the Balkans. Media reports said the suspect had a license for the handgun.
Residents said Bogdanovic first killed his son and his mother before leaving his house and then began shooting his neighbors. They expressed deep shock, describing the suspect as a nice, quiet man.
"He knocked on the doors and as they were opened he just fired a shot," said villager Radovan Radosavljevic. "He was a good neighbor and anyone would open their doors to him. I don't know what happened."
"I never saw him angry, ever," said Milovan Kostadinovic, another resident. "He was helping everybody, he had a car and drove us everywhere."
Still, neighbors said an entire five-member family was shot dead in one house, including the small boy who was the suspected killer's cousin.
Kostadinovic said the suspect was confronted by police while en route to his house.
"If they didn't stop him, he would have wiped us all out," Kostadinovic said, standing in front of his two-story, red tile- roofed house. "He shot himself when police stopped him."
His wife Stanica said their small white-and-brown dog Rocky had gotten very nervous early in the morning and was barking and jumping up and down. She said when her husband opened their door, a policewoman shouted: "Get back in!"
"He was shooting everybody. Police saved us," she said.
The suspected killer owned a gun but neighbors and his brother said he never hunted or shot weapons, even at weddings or celebrations as is traditional in the Balkans.
"He was quiet as a bug," Stanica Kostadinovic said.
Nada Macura, a Belgrade hospital spokeswoman, said the suspect had no known history of mental illness. Stanica Kostadinovic, the neighbor, said the man's father had hanged himself when he was a young boy and his uncle had a history of mental illness.
Police blocked off the village while forensic teams and investigators in white protective robes took evidence from homes where the shootings took place.
Doctors said later the suspect's condition was critical but his wife was able to communicate with the hospital staff.
Serbian Prime Minister Ivica Dacic said the killings showed that the government must pay more attention to gun control and other social problems facing the Balkan nation, which is still reeling from the 1990s wars. His government held an emergency session and was expected to proclaim a national day of mourning.
Serbia's last big shooting spree occurred in 2007, when a 39-year-old man gunned down nine people and injured two others in the eastern village of Jabukovac.
__
Sabina Niksic contributed from Bosnia.
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WASHINGTON (AP) ? Virgin America did the best job for its customers among leading U.S. airlines last year, a report said Monday, as carriers overall had their second best performance in the more than the two decades since researchers began measuring quality of service.
The report ranked the 14 largest U.S. airlines based on on-time arrivals, mishandled bags, consumer complaints and passengers who bought tickets but were turned away because flights were over booked.
Airline performance in 2012 was the second highest in the 23 years that Wichita State University in Kansas and the University of Nebraska at Omaha have tracked the performance of airlines. The airline's best year was 2011.
Besides being the overall leader, Virgin America, headquartered in Burlingame, Calif., also did the best job on baggage handling and had the second-lowest rate of passengers denied seats due to overbookings. United Airlines, whose consumer complaint rate nearly doubled last year, had the worst performance. United has merged with Continental Airlines, but has had rough spots in integrating the operations of the two carriers.
The number of complaints consumers filed with the Department of Transportation overall surged by one-fifth last year to 11,445 complaints, up from 9,414 in 2011.
"Over the 20-some year history we've looked at it, this is still the best time of airline performance we've ever seen," said Dean Headley, a business professor at Wichita State University in Kansas, who has co-written the annual report. The best year was 2011, which was only slightly better than last year, he said.
Despite those improvements, it's not surprising that passengers are getting grumpier, Headley said. Carriers keep shrinking the size of seats in order to stuff more people into planes. Empty middle seats that might provide a little more room have vanished. And more people who have bought tickets are being turned away because flights are overbooked.
"The way airlines have taken 130-seat airplanes and expanded them to 150 seats to squeeze out more revenue, I think, is finally catching up with them," he said. "People are saying, 'Look, I don't fit here. Do something about this.' At some point airlines can't keep shrinking seats to put more people into the same tube," he said.
The industry is even looking at ways to make today's smaller-than-a-broom closet toilets more compact in the hope of squeezing a few more seats onto planes.
"I can't imagine the uproar that making toilets smaller might generate," Headley said, especially given that passengers increasingly weigh more than they use to. Nevertheless, "will it keep them from flying? I doubt it would."
The rate of complaints per 100,000 passengers also rose to 1.43 last year from 1.19 in 2011.
United's 2012 ranking doesn't reflect its experience over the past six months, in which the airline has made significant improvements in performance, company spokesman Rahsaan Johnson said
"Customer satisfaction is up, complaints are down dramatically and we are improving our customers' experience," he said in an email.
In recent years, some airlines have shifted to larger planes that can carry more people, but that hasn't been enough to make up for an overall reduction in flights.
The rate at which passengers with tickets were denied seats because planes were full rose to 0.97 denials per 10,000 passengers last year, compared with 0.78 in 2011.
It used to be in cases of overbookings that airlines usually could find a passenger who would volunteer to give up a seat in exchange for cash, a free ticket or some other compensation with the expectation of catching another flight later that day or the next morning. Not anymore.
"Since flights are so full, there are no seats on those next flights. So people say, 'No, not for $500, not for $1,000,' " said airline industry analyst Robert W. Mann Jr.
Regional carrier SkyWest had the highest involuntary denied-boardings rate last year, 2.32 per 10,000 passengers.
But not every airline overbooks flights in an effort to keep seats full. JetBlue and Virgin America were the industry leaders in avoiding denied boardings, with rates of 0.01 and 0.07, respectively.
United Airlines' consumer complaint rate was 4.24 complaints per 100,000 passengers. Southwest had the lowest rate, at 0.25. Southwest was among five airlines that lowered complaint rates last year compared to 2011. The others were American Eagle, Delta, JetBlue and US Airways.
Consumer complaints were significantly higher in the peak summer travel months of June, July and August when planes are especially crowded.
"As airplanes get fuller, complaints get higher because people just don't like to be sardines," Mann said.
The complaints are regarded as indicators of a larger problem because many passengers may not realize they can file complaints with the Transportation Department, which regulates airlines.
At the same time that complaints were increasing, airlines were doing a better job of getting passengers to their destinations on time.
The industry average for on-time arrival rates was 81.8 percent of flights, compared with 80 percent in 2011. Hawaiian Airlines had the best on-time performance record, 93.4 percent in 2012. ExpressJet and American Airlines had the worst records with only 76.9 percent of their planes arriving on time last year.
The industry's on-time performance has improved in recent years, partly due to airlines' decision to cut back on the number of flights.
"We've shown over the 20 years of doing this that whenever the system isn't taxed as much ? fewer flights, fewer people, less bags ? it performs better. It's when it reaches a critical mass that it starts to fracture," Headley said.
The industry's shift to charging for fees for extra bags, or sometimes charging fees for any bags, has significantly reduced the rate of lost or mishandled bags. Passengers are checking fewer bags than before, and carrying more bags onto planes when permitted.
The industry's mishandled bag rate peaked in 2007 at 7.01 mishandled bags per 1,000 passengers. It was 3.07 in 2012, down from 3.35 bags the previous year.
The report's ratings are based on statistics kept by the department for airlines that carry at least 1 percent of the passengers who flew domestically last year.
___
Follow Joan Lowy on Twitter: http://www.twitter.com/AP_Joan_Lowy
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Price tags aside, what kind of skin care products would achieve the best results for my skin? (mainly the face) I have been sticking to natural raw products such as coconut oil lately, but I am curious as to if expensive products are more effective.
For different type of skin, there are different skin care products. You always need to carefully choose product for your skin. It can be harmful. Though natural products are very good but take time, while other luxury product works instantly. You can find instant change in your skin. So its depend on you what you want.
by: Geeb Seye
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Gentle Scrub, from organic skin care company Marie Veronique Organics: Gently removes excess dead skin cells that build up on the skin?s surface, Scrubs without stripping or irritating the skin with rice bran, marshmallow root and adzuki bean powders, Does not contain sharp granules that can create microscopic tears and abrasions which expose the skin to bacterial infections, Naturally soothes and softens skin with green tea, jade, oatmeal, and aloe.
Date Taken: 2010-08-27 07:40:54
Owner: Marie Veronique Organics
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ACM Award Winners 2013! Stupid Celebrities Gossip Stupid Celebrities Gossip News
Source: http://stupidcelebrities.net/2013/04/acm-award-winners-2013/
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Acer doesn't seem to have officially announced the Iconia tab A1-810 yet... at least not that we can see. But French retailer Rue Du Commerce already has the 7.9 inch listed, though, since it was first spotted the spec sheet has been cleared. Thankfully, MiniMachines caught the page before someone scrubbed it clean. If the numbers are to be believed, then the Taiwanese company has the Nexus 7 and iPad mini squarely in its sights. The A1-810's crams some reasonably impressive internals into a diminutive and affordable package. Under the hood is 1GB of RAM, and a 1.2GHz quad-core processor. Granted, the Cortex-A9 chip is produced by MediaTek instead of one of the bigger boys like Qualcomm or NVIDIA, but it should prove plenty robust for everyday tasks. The 1024 x 768 IPS panel puts it right in league with Apple's mini, but it also means a lower pixel density than the middle child of the Nexus family. You'll also find 802.11n, Bluetooth 4.0 and GPS radios inside, along with a 3,250 mAh battery -- which is quite a bit smaller than its competitors (despite its 10.5mm thick, 430g body being quite a bit larger). The biggest news about this Android 4.2 device though, is the price: it's yet another uber-cheap slate, currently listed at €199, or about $259.
Filed under: Tablets
Via: Android Authority, MiniMachines
Source: Rue Du Commerce
Source: http://www.engadget.com/2013/04/08/acers-iconia-a1-810/
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Biologist Kaleigh LaRiche spent most of her first two years after college working in wildlife education at the Akron, Ohio, zoo. Today, she's a first-year science teacher in a Cleveland middle school.
LaRiche, who earns her master's in education from the University of Akron this spring, thanks the Woodrow Wilson Teaching Fellowship for her confidence in the classroom. The two-year master's program recruits accomplished science, technology, engineering and math (STEM) college graduates, as well as career changers like LaRiche, and puts them through their paces in preparation to work in high-need schools.
[Explore the Best Education Schools rankings.]
It is one of several model programs leading the charge to fulfill President Barack Obama's call for 100,000 highly qualified STEM teachers over the next decade, and to get them ready for the much-anticipated new K-12 math and science standards. With only 26 percent of U.S. 12th graders now deemed proficient in math, most states have adopted more rigorous new Common Core Standards for what kids should master at each level.
These guidelines stress depth over breadth; a separate effort, the Next Generation Science Standards, emphasizes questioning and discovery rather than rote memorization.
The Wilson Fellowship partners with several graduate schools of education in Ohio, Indiana, Michigan and New Jersey, including the University of Indianapolis, Ball State University, the University of Michigan, Wayne State University and Montclair State University.
Almost from the start, fellows are immersed for the school year in local K-12 classrooms. LaRiche's four-day-a-week internship at a Canton, Ohio, middle school provided a $30,000 stipend and two mentors to show her the ropes. Course work included classes in the biology department and on problem- and project-based learning.
LaRiche is now a licensed teacher at Cleveland's Harvard Avenue Community School. When covering renewable and non-renewable energy in her sixth grade science class, she breaks students into groups and has them examine which renewable energy alterative would work best for a fictitious town and why.
"They are not used to learning this way," she says. "They are used to a teacher lecturing, taking notes, doing worksheets and labs." The goal is to make clear that science is a process.
Such innovations reflect the latest thinking about what is needed to put better science and math teachers - all kinds of teachers, in fact - into classrooms: an emphasis on subject content knowledge, abundant field experience and high-caliber candidates, as outlined in a 2010 National Research Council report.
Additionally, teacher-prep programs are creating subject-specific methods courses - so a biology candidate can study how best to teach biology, say - that provide training in problem-solving and project-based instruction.
"Woodrow Wilson really opened us to innovation and thinking creatively," says Jennifer Drake, dean of the college of arts and sciences at the University of Indianapolis. The university therefore has embedded intensive hands-on practice in all of its teacher-prep programs, is moving to require elementary-ed candidates to take more math and science courses and has deepened cross-pollination between the arts and sciences and education schools.
"In math, there is always a right answer, but there are always different ways to get there," says Christopher Lewine, a third-year teacher in Redwood City, Calif. So instead of moving to the next problem when a correct answer is given to an algebraic problem, Lewine's class at Everest Public High School is just getting started.
Rather than lecturing, he prompts students to discuss and defend how they solved the problem, discovering different approaches from one another. He learned this technique while getting his master's in the yearlong practice-heavy Teacher Education Program at Stanford University.
[Stay up to date with the High School Notes blog.]
Though the pace of innovation has picked up, teacher-prep programs vary widely in quality, and far too many still prepare teachers in a bubble, disconnected from the realities of the classroom, says Arthur Levine, president of the Woodrow Wilson National Fellowship Foundation and author of "Educating School Teachers," a milestone 2006 report.
You want "strong support in a total immersion program," preferably one that partners with K-12 schools and provides teacher-mentors, says Charles Coble, co-director of an Association of Public and Land-Grant Universities initiative to overhaul teacher training. That effort, the Science & Math Teacher Imperative, has sparked a move toward these sorts of best practices at 132 public and flagship universities and 13 university systems, which together produce more than 40 percent of the nation's math and science teachers.
Some of the new master's options aimed at scientists and mathematicians are modeled on the clinical training medical residents get. Kevin Perry was headed for a career in surgery when he decided he'd rather teach middle-school biology in New York City instead. He gets his teaching certification in middle- and high-school science this summer after a year in New York University's Clinically Rich Integrated Science Program (CRISP).
"On the second day of the program, we were put in the classroom," Perry says. After several weeks observing during a summer session last July, he was paired with a biology teacher in September to observe and then begin co-teaching at East Side Community School in Manhattan.
Each week, Perry and fellow teaching residents are led by NYU and K-12 school faculty in instructional "rounds" in which they discuss what works and what doesn't. He also takes courses in science, teaching methods, literacy and language acquisition and data and assessment.
Perry receives $30,000 in scholarships from NYU's Steinhart school and New York State, along with a $20,000 living stipend. Similar residencies are offered by the University of Pennsylvania, University of Delaware and Georgia State University, among many others.
[Discover ways to pay for graduate school.]
How can current teachers beef up their STEM bona fides and get set for the coming standards? Part-time and online options are springing up to meet their needs.
The University of Maryland, for example, has created a teacher-oriented master's of education in middle-school mathematics.
"This truly has made me a better teacher," says Germantown, Md., algebra teacher Adam Ritchie, who finished the Maryland evening and summer program in December. "I was able to apply [course work] right off the bat in the classroom."
Besides studies that encouraged exploratory and inquiry-based learning and gave him the know-how to better challenge all kids regardless of ability, Ritchie took algebra, geometry and statistics, and now feels much more ready for the Common Core in math, which gets rolled out in county middle schools next year.
The other welcome payoff: a 20 percent bump in salary.
This story is excerpted from the U.S. News Best Graduate Schools 2014 guidebook, which features in-depth articles, rankings, and data.
Source: http://news.yahoo.com/education-schools-innovate-supply-stem-teachers-144757267.html
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You may not look at the trio of concentric seats above and think "expensive electronic car," but French designers Ronan and Erwan Bouroullec are nonetheless calling their "Quiet Motion" exhibit at this year's Solone del Mobile an "allegorical interpretation" of just that. Beyond simply looking pretty, the exhibit is intended to represent BMW's history of working with "designers spanning a wide range of industries" -- BMW's long-running Art Car project, for instance -- as well as employ the sustainable materials used in the BMWi line. They're calling the slowly rotating platforms a version of a carousel, and you'll be able to get your gluteus maximus on the installation starting tomorrow through April 14th. Whether it inspires you to buy a BMWi vehicle ... well, that's another question; at very least, it's a rather unique photo opp (if you're in Milan, that is).
Filed under: Transportation, Alt
Source: http://www.engadget.com/2013/04/08/bmwi-quiet-motion/
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JERUSALEM (AP) ? The Israeli military says its chief of staff will head a delegation to a Holocaust memorial at the site of the Nazi death camp Auschwitz.
Lt. Gen. Benny Gantz, the son of Holocaust survivors, left for Poland Sunday as Israel prepared for its Holocaust and Heroism Remembrance Day commemorations.
Six million Jews were systematically murdered by German Nazis and their collaborators in the Holocaust of World War II, wiping out a third of world Jewry.
The Israeli military said Gantz will be welcomed in a military ceremony.
Gantz will later meet with Poland's defense minister and chief of staff.
He will place a wreath on the Tomb of the Unknown Soldier in Warsaw, the military said.
Source: http://news.yahoo.com/israels-military-chief-visit-auschwitz-064729295.html
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WASHINGTON (AP) ? Secretary of State John Kerry headed to the Middle East on Saturday, his third trip to the region in two weeks, in a fresh bid to unlock long-stalled Israeli-Palestinian peace talks.
Istanbul was the first leg of a six-nation trip that will see him travel on to Europe and Asia.
From Turkey, he planned to go to Jerusalem for meetings with the presidents and prime ministers of both Israel and the Palestinians. Kerry accompanied President Barack Obama there last month and made a solo trip to Israel shortly after.
Though expectations are low for any breakthrough on Kerry's trip, his diplomacy represents some of the Obama administration's most sustained efforts for ending more than six decades of conflict between Israelis and Palestinians.
Kerry probably will seek confidence-building measures between the two sides. Negotiators and observers see little chance right now for immediate progress on the big stumbling blocks toward a two-state peace agreement.
He may have more success on his first stop persuading Turkish leaders to continue improving ties with Israel. The two countries were once allies, but relations spiraled downward after Israel's 2010 raid on a Turkish flotilla bound for the Gaza Strip. Eight Turks and one Turkish-American died.
Hopes for rapprochement improved after Obama brokered a telephone conversation between Israeli Prime Minister Benjamin Netanyahu and Turkey's prime minister, Recep Tayyip Erdogan, while Obama was in Israel.
In Turkey, Kerry also will coordinate with Erdogan and other Turkish officials on efforts to halt the violence in neighboring Syria.
Kerry will also visit Britain and then South Korea, China and Japan, where talks will focus on North Korea's nuclear program and escalating threats against the U.S. and its allies.
He is scheduled to return to Washington on April 15.
Source: http://news.yahoo.com/kerry-heads-back-mideast-fresh-peace-push-083435451--politics.html
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Does anyone know this system and know where to insert the Google Analytics code on the back-end? I've looked on the CMS forum but the only result for this is a google plug-in which is no longer being developed, thanks. Just looking for simple instructions ie which area to insert the code. __________________Sarah Olney SO Direct Digital Marketer and PR consultant 35 years' experience email: sarah.olney@sodirect.org If you are divorced, bringing up children, want to learn about Internet Marketing, blog to promote your business and earn a second income. Please message me or see: http://www.empowernetwork.com/sodirect
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Can you edit the templates to add it in manually? __________________Find Items Online For Less! Simply type the item in and it will compare prices on over 8 million items and 950 online stores!! |
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Try following: -Login into administration area -Find "Layout" tab -Select "Templates" -Next to each template record there is a "Edit" button. Click it. -Somewhere at the bottom there is tag: " Keep in mind that you need to do this for each of your template records.
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I am moving to a new website on my .co.uk but would like to keep this site and turn it into educational papers, frustrating that I can't load the analytics on my own website, as it's such a basic! __________________Sarah Olney SO Direct Digital Marketer and PR consultant 35 years' experience email: sarah.olney@sodirect.org If you are divorced, bringing up children, want to learn about Internet Marketing, blog to promote your business and earn a second income. Please message me or see: http://www.empowernetwork.com/sodirect
Last edited by sodirect; Yesterday at 12:02. Reason: insert title |
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You need to add in GA MADE SIMPLE module or other similar module. A web dev can do it for you or even add custom code to the template.It should be fairly easy for them and not cost much. |
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Sarah, try this plugin or to add it into the site manually: Layouts > templates > choose the "default" template > scroll to the bottom of the code and look for the </body> and add the GA code right above it e.g. Code: <script type="text/javascript"> // stuff </script> </body> </html> |
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I fail to see reason to post same solution after someone answered the question... |
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2) Because I showed a code snippet to make it easier to understand 3) Because I linked to a relevant plugin which is helpful Is that enough reasons? |
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It's not, for few reasons. re 1) Your fault. re 2) Your personal opinion. re 3) Seems like you also haven't see the question properly. It states - no plugins. But anyhow, important thing is that we provided the answer to the question...
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All times are GMT. The time now is 13:25.
Source: http://www.ukbusinessforums.co.uk/forums/showthread.php?t=293136
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Apr. 5, 2013 ? A new paper led by a NASA researcher shows that hydrogen peroxide is abundant across much of the surface of Jupiter's moon Europa. The authors argue that if the peroxide on the surface of Europa mixes into the ocean below, it could be an important energy supply for simple forms of life, if life were to exist there.
The paper was published online recently in the Astrophysical Journal Letters.
"Life as we know it needs liquid water, elements like carbon, nitrogen, phosphorus and sulfur, and it needs some form of chemical or light energy to get the business of life done," said Kevin Hand, the paper's lead author, based at NASA's Jet Propulsion Laboratory, Pasadena, Calif. "Europa has the liquid water and elements, and we think that compounds like peroxide might be an important part of the energy requirement. The availability of oxidants like peroxide on Earth was a critical part of the rise of complex, multicellular life."
The paper, co-authored by Mike Brown of the California Institute of Technology in Pasadena, analyzed data in the near-infrared range of light from Europa, using the Keck II Telescope on Mauna Kea, Hawaii, over four nights in September 2011. The highest concentration of peroxide found was on the side of Europa that always leads in its orbit around Jupiter, with a peroxide abundance of 0.12 percent relative to water. (For perspective, this is roughly 20 times more diluted than the hydrogen peroxide mixture available at drug stores.) The concentration of peroxide in Europa's ice then drops off to nearly zero on the hemisphere of Europa that faces backward in its orbit.
Hydrogen peroxide was first detected on Europa by NASA's Galileo mission, which explored the Jupiter system from 1995 to 2003, but Galileo observations were of a limited region. The new results show that peroxide is widespread across much of the surface of Europa, and the highest concentrations are reached in regions where Europa's ice is nearly pure water with very little sulfur contamination. The peroxide is created by the intense radiation processing of Europa's surface ice that comes from the moon's location within Jupiter's strong magnetic field.
"The Galileo measurements gave us tantalizing hints of what might be happening all over the surface of Europa, and we've now been able to quantify that with our Keck telescope observations," Brown said. "What we still don't know is how the surface and the ocean mix, which would provide a mechanism for any life to use the peroxide."
The scientists think hydrogen peroxide is an important factor for the habitability of the global liquid water ocean under Europa's icy crust because hydrogen peroxide decays to oxygen when mixed into liquid water. "At Europa, abundant compounds like peroxide could help to satisfy the chemical energy requirement needed for life within the ocean, if the peroxide is mixed into the ocean," said Hand.
The study was funded in part by the NASA Astrobiology Institute through the Icy Worlds team based at JPL, a division of Caltech. The NASA Astrobiology Institute, based at NASA's Ames Research Center, Moffett Field, Calif., is a partnership among NASA, 15 U.S. teams and 13 international consortia. The Institute is part of NASA's astrobiology program, which supports research into the origin, evolution, distribution and future of life on Earth and the potential for life elsewhere.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/space_time/astronomy/~3/lZA_bx0his8/130405143418.htm
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Facebook's popularity keeps climbing in terms of new members, but some say 'Facebook fatigue' or 'News Feed overload' make visiting the site a chore.
Daniel Singer, 13. works at his computer in Los Angeles, March 25. Singer says teens want to see new stuff on Facebook. Facebook is part of a daily routine, he says, 'kind of like brushing your teeth.'
Nick Ut / AP
EnlargeTo see what Facebook has become, look no further than the Hutzler 571 Banana Slicer.
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Sometime last year, people began sharing tongue-in-cheek online reviews of the banana-shaped piece of yellow plastic with their Facebook friends. Then those friends shared with their friends. Soon, after Amazon paid to promote it, posts featuring the $3.49 utensil were appearing in even more Facebook feeds.
At some point, though, the joke got old. But there it was, again and again ? the banana slicer had become a Facebook version of that old knock-knock joke your weird uncle has been telling for years.
The Hutzler 571 phenomenon is a regular occurrence on the world's biggest online social network, which begs the question: Has Facebook become less fun?
That's something many users ? especially those in their teens and early 20s ? are asking themselves as they wade through endless posts, photos "liked" by people they barely know and spur-of-the moment friend requests. Has it all become too much of a chore? Are the important life events of your closest loved ones drowning in a sea of banana slicer jokes?
"When I first got Facebook I literally thought it was the coolest thing to have. If you had a Facebook you kind of fit in better, because other people had one," says Rachel Fernandez, 18, who first signed on to the site four or five years ago.
And now? "Facebook got kind of boring," she says.
Chatter about Facebook's demise never seems to die down, whether it's talk of "Facebook fatigue," or grousing about how the social network lost its cool once grandma joined. The Pew Research Center's Internet and American Life Project recently found that some 61 percent of Facebook users had taken a hiatus from the site for reasons that range from "too much gossip and drama" to "boredom." Some respondents said there simply isn't enough time in their day for Facebook.
If Facebook Inc.'s users leave, or even check in less frequently, its revenue growth would suffer. The company, which depends on targeted advertising for most of the money it makes, booked revenue of $5.1 billion in 2012, up from $3.7 billion a year earlier.
But so far, for every person who has left permanently, several new people have joined up. Facebook has more than 1 billion users around the world. Of these, 618 million sign in every day.
Indeed, Fernandez hasn't abandoned Facebook. Though the Traverse City, Mich., high school senior doesn't look at her News Feed, the constant cascade of posts, photos and viral videos from her nearly 1,800 friends, she still uses Facebook's messaging feature to reach out to people she knows, such as a German foreign exchange student she met two years ago.
Fernandez uses Facebook in the same way that people use email or the telephone. But she prefers using Facebook to communicate because everyone she knows is there. That's a sign that Facebook's biggest asset may also be its biggest challenge.
"We have never seen a social space that actually works for everybody," says danah boyd, who studies youth culture, the Internet and social media as a senior researcher at Microsoft Research. "People don't want to hang out with everybody they have ever met."
Might Facebook go the way of email? Those who came of age in the "You've got mail" era can reminisce fondly about arriving home from school and checking their AOL accounts to see if anyone sent them an electronic message. Boyd, who is 35 (and legally spells her name with no capitalization), recalls being a teenager and "thinking email is the best thing ever."
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/2tDYtMqmFZo/As-Facebook-matures-is-it-getting-less-fun
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Public release date: 6-Apr-2013
Share ] Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-634-7302
Genetics Society of America
Washington, D.C. (April 6, 2013) Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease (PD) using a common sweetener, mannitol. This research is presented today at the Genetics Society of America's 54th Annual Drosophila Research Conference in Washington D.C., April 3-7, 2013.
Mannitol is a sugar alcohol familiar as a component of sugar-free gum and candies. Originally isolated from flowering ash, mannitol is believed to have been the "manna" that rained down from the heavens in biblical times. Fungi, bacteria, algae, and plants make mannitol, but the human body can't. For most commercial uses it is extracted from seaweed although chemists can synthesize it. And it can be used for more than just a sweetener.
The Food and Drug Administration approved mannitol as an intravenous diuretic to flush out excess fluid. It also enables drugs to cross the blood-brain barrier (BBB), the tightly linked cells that form the walls of capillaries in the brain. The tight junctions holding together the cells of these tiniest blood vessels come slightly apart five minutes after an infusion of mannitol into the carotid artery, and they stay open for about 30 minutes.
Mannitol has another, less-explored talent: preventing a sticky protein called ?-synuclein from gumming up the substantia nigra part of the brains of people with PD and Lewy body dementia (LBD), which has similar symptoms to PD. In the disease state, the proteins first misfold, then form sheets that aggregate and then extend, forming gummy fibrils.
Certain biochemicals, called molecular chaperones, normally stabilize proteins and help them fold into their native three-dimensional forms, which are essential to their functions. Mannitol is a chemical chaperone. So like a delivery person who both opens the door and brings in the pizza, mannitol may be used to treat Parkinson's disease by getting into the brain and then restoring normal folding to ?-synuclein.
Daniel Segal, PhD, and colleagues at Tel Aviv University investigated the effects of mannitol on the brain by feeding it to fruit flies with a form of PD that has highly aggregated ?-synuclein.
The researchers used a "locomotion climbing assay" to study fly movement. Normal flies scamper right up the wall of a test tube, but flies whose brains are encumbered with ?-synuclein aggregates stay at the bottom, presumably because they can't move normally. The percentage of flies that climb one centimeter in 18 seconds assesses the effect of mannitol.
An experimental run tested flies daily for 27 days. After that time, 72% of normal flies climbed up, in comparison to 38% of the PD flies. Their lack of ascension up the sides of the test tube indicated "severe motor dysfunction."
In contrast, were flies bred to harbor the human mutant ?-synuclein gene, who as larvae feasted on mannitol that sweetened the medium at the bottoms of their vials. These flies fared much better -- 70% of them could climb after 27 days. And slices of their brains revealed a 70% decrease in accumulated misfolded protein compared to the brains of mutant flies raised on the regular medium lacking mannitol.
It's a long way from helping climbing-impaired flies to a new treatment for people, but the research suggests a possible novel therapeutic direction. Dr. Segal, however, cautioned that people with PD or similar movement disorders should not chew a ton of mannitol-sweetened gum or sweets; that will not help their current condition. The next step for researchers is to demonstrate a rescue effect in mice, similar to improved climbing by flies, in which a rolling drum ("rotarod") activity assesses mobility.
"Until and if mannitol is proven to be efficient for PD on its own, the more conservative and possibly more immediate use can be the conventional one, using it as a BBB disruptor to facilitate entrance of other approved drugs that have problems passing through the BBB," Dr. Segal said. A preliminary clinical trial of mannitol on a small number of volunteers might follow if results in mice support those seen in the flies, he added, but that is still many research steps away.
Session Title: Drosophila Models of Human Diseases I
Program #91 -- Date and Time: Saturday, April 6, 2013; 8:30-8:45 AM
Location: Marriott Wardman Park, Marriott Ballroom Salon 1, Lobby Level
Mannitol -- a BBB disrupter is also a potent ?-synuclein aggregation inhibitro for treating Parkinson's disease. Daniel Segal1,2, Ronit Shaltiel-Karyo1, Moran Frenkel-Pinter1, Edward Rockenstein3, Christina Patrick3, Michal Levy-Sakin1, Nirit Egoz-Matia1, Eliezer Masliah3, Ehud Gazit1. 1) Department of Molecular Microbiol & Biotech, Tel Aviv University, Tel Aviv 69978, Israel; 2) Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 69978, Israel; 3) Department of Neurosciences, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
###
FOR MEMBERS OF THE MEDIA: The 54th Annual Drosophila Research Conference is open to print, online and broadcast news media and freelance science, medical and health writers on a verifiable assignment from an established news source. If you would like to attend all or part of the Conference, complimentary meeting registration is available to members of the media who provide appropriate press credentials and identification. Please contact: Phyllis Edelman, GSA Communications and Public Relations Manager, pedelman@genetics-gsa.org, or phone: 301-351-0896.
ABOUT THE GSA DROSOPHILA RESEARCH CONFERENCE: Nearly 1,500 researchers attend the annual GSA Drosophila Research Conference to share the latest research using the fruit fly Drosophila melanogaster and other insect species. Many of findings from these model organisms have broad application for the study of human genetic traits and diseases. For more information about the conference, see http://www.dros-conf.org/2013/
ABOUT GSA: Founded in 1931, the Genetics Society of America (GSA) is the professional membership organization for scientific researchers, educators, bioengineers, bioinformaticians and others interested in the field of genetics. Its nearly 5,000 members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level. The GSA is dedicated to promoting research in genetics and to facilitating communication among geneticists worldwide through its conferences, including the biennial conference on Model Organisms to Human Biology, an interdisciplinary meeting on current and cutting edge topics in genetics research, as well as annual and biennial meetings that focus on the genetics of particular organisms, including C. elegans, Drosophila, fungi, mice, yeast, and zebrafish. GSA publishes GENETICS, a leading journal in the field and a new online, open-access publication, G3: Genes|Genomes|Genetics. For more information about GSA, please visit http://www.genetics-gsa.org. Also follow GSA on Facebook at facebook.com/GeneticsGSA and on Twitter @GeneticsGSA.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 6-Apr-2013 Share ] Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-634-7302
Genetics Society of America
Washington, D.C. (April 6, 2013) Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease (PD) using a common sweetener, mannitol. This research is presented today at the Genetics Society of America's 54th Annual Drosophila Research Conference in Washington D.C., April 3-7, 2013.
Mannitol is a sugar alcohol familiar as a component of sugar-free gum and candies. Originally isolated from flowering ash, mannitol is believed to have been the "manna" that rained down from the heavens in biblical times. Fungi, bacteria, algae, and plants make mannitol, but the human body can't. For most commercial uses it is extracted from seaweed although chemists can synthesize it. And it can be used for more than just a sweetener.
The Food and Drug Administration approved mannitol as an intravenous diuretic to flush out excess fluid. It also enables drugs to cross the blood-brain barrier (BBB), the tightly linked cells that form the walls of capillaries in the brain. The tight junctions holding together the cells of these tiniest blood vessels come slightly apart five minutes after an infusion of mannitol into the carotid artery, and they stay open for about 30 minutes.
Mannitol has another, less-explored talent: preventing a sticky protein called ?-synuclein from gumming up the substantia nigra part of the brains of people with PD and Lewy body dementia (LBD), which has similar symptoms to PD. In the disease state, the proteins first misfold, then form sheets that aggregate and then extend, forming gummy fibrils.
Certain biochemicals, called molecular chaperones, normally stabilize proteins and help them fold into their native three-dimensional forms, which are essential to their functions. Mannitol is a chemical chaperone. So like a delivery person who both opens the door and brings in the pizza, mannitol may be used to treat Parkinson's disease by getting into the brain and then restoring normal folding to ?-synuclein.
Daniel Segal, PhD, and colleagues at Tel Aviv University investigated the effects of mannitol on the brain by feeding it to fruit flies with a form of PD that has highly aggregated ?-synuclein.
The researchers used a "locomotion climbing assay" to study fly movement. Normal flies scamper right up the wall of a test tube, but flies whose brains are encumbered with ?-synuclein aggregates stay at the bottom, presumably because they can't move normally. The percentage of flies that climb one centimeter in 18 seconds assesses the effect of mannitol.
An experimental run tested flies daily for 27 days. After that time, 72% of normal flies climbed up, in comparison to 38% of the PD flies. Their lack of ascension up the sides of the test tube indicated "severe motor dysfunction."
In contrast, were flies bred to harbor the human mutant ?-synuclein gene, who as larvae feasted on mannitol that sweetened the medium at the bottoms of their vials. These flies fared much better -- 70% of them could climb after 27 days. And slices of their brains revealed a 70% decrease in accumulated misfolded protein compared to the brains of mutant flies raised on the regular medium lacking mannitol.
It's a long way from helping climbing-impaired flies to a new treatment for people, but the research suggests a possible novel therapeutic direction. Dr. Segal, however, cautioned that people with PD or similar movement disorders should not chew a ton of mannitol-sweetened gum or sweets; that will not help their current condition. The next step for researchers is to demonstrate a rescue effect in mice, similar to improved climbing by flies, in which a rolling drum ("rotarod") activity assesses mobility.
"Until and if mannitol is proven to be efficient for PD on its own, the more conservative and possibly more immediate use can be the conventional one, using it as a BBB disruptor to facilitate entrance of other approved drugs that have problems passing through the BBB," Dr. Segal said. A preliminary clinical trial of mannitol on a small number of volunteers might follow if results in mice support those seen in the flies, he added, but that is still many research steps away.
Session Title: Drosophila Models of Human Diseases I
Program #91 -- Date and Time: Saturday, April 6, 2013; 8:30-8:45 AM
Location: Marriott Wardman Park, Marriott Ballroom Salon 1, Lobby Level
Mannitol -- a BBB disrupter is also a potent ?-synuclein aggregation inhibitro for treating Parkinson's disease. Daniel Segal1,2, Ronit Shaltiel-Karyo1, Moran Frenkel-Pinter1, Edward Rockenstein3, Christina Patrick3, Michal Levy-Sakin1, Nirit Egoz-Matia1, Eliezer Masliah3, Ehud Gazit1. 1) Department of Molecular Microbiol & Biotech, Tel Aviv University, Tel Aviv 69978, Israel; 2) Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 69978, Israel; 3) Department of Neurosciences, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
###
FOR MEMBERS OF THE MEDIA: The 54th Annual Drosophila Research Conference is open to print, online and broadcast news media and freelance science, medical and health writers on a verifiable assignment from an established news source. If you would like to attend all or part of the Conference, complimentary meeting registration is available to members of the media who provide appropriate press credentials and identification. Please contact: Phyllis Edelman, GSA Communications and Public Relations Manager, pedelman@genetics-gsa.org, or phone: 301-351-0896.
ABOUT THE GSA DROSOPHILA RESEARCH CONFERENCE: Nearly 1,500 researchers attend the annual GSA Drosophila Research Conference to share the latest research using the fruit fly Drosophila melanogaster and other insect species. Many of findings from these model organisms have broad application for the study of human genetic traits and diseases. For more information about the conference, see http://www.dros-conf.org/2013/
ABOUT GSA: Founded in 1931, the Genetics Society of America (GSA) is the professional membership organization for scientific researchers, educators, bioengineers, bioinformaticians and others interested in the field of genetics. Its nearly 5,000 members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level. The GSA is dedicated to promoting research in genetics and to facilitating communication among geneticists worldwide through its conferences, including the biennial conference on Model Organisms to Human Biology, an interdisciplinary meeting on current and cutting edge topics in genetics research, as well as annual and biennial meetings that focus on the genetics of particular organisms, including C. elegans, Drosophila, fungi, mice, yeast, and zebrafish. GSA publishes GENETICS, a leading journal in the field and a new online, open-access publication, G3: Genes|Genomes|Genetics. For more information about GSA, please visit http://www.genetics-gsa.org. Also follow GSA on Facebook at facebook.com/GeneticsGSA and on Twitter @GeneticsGSA.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/gsoa-fma032913.php
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